PNOC Foundation - Lose No Child to Brain Cancer

Startup

There has never been a more hopeful time in history to invest in childhood cancer research.

Brain cancer is the deadliest childhood cancer, the Pediatric Neuro-oncology Consortium (PNOC) brings together the world's best 300+ clinicians and researchers to push for breakthroughs.

A scientific consortium with a global presence, PNOC unites the world's leading hospitals in an unprecedented collaboration to find cures and save lives.

Lose No Child is our bold and urgent $50 million campaign driving progress to transform treatment, advance research, and develop safer, more effective therapies for kids with brain cancer.

Your gift will help us reach a future where we lose no child to brain cancer.

We are a GuideStar platinum rated registered 501(c)3, and proud to be one of San Francisco's 2025 Philanthropy Award Winners.

When a family first hears that their child has a brain tumor, their whole world is changed. Fast, complex decisions must be made while they are still shocked by an unimaginable diagnosis. Unfortunately for a lot of pediatric brain tumor diagnoses, there is no standard of care.

In 2010 our son George started experiencing morning headaches and nausea. He was diagnosed with a brain tumor, an ependymoma, the size of a small orange, located on the right side of his brain. George underwent 10 hours of surgery and 31 sessions of subsequent radiation therapy. George is now in college and we know we are blessed. We pledge to make the difference in the lives of other children and their families affected by brain tumors by raising awareness and funds for research and clinical trials.

When our own son George was diagnosed with brain cancer, treatment options were limited – there was no precision medicine, no genetic sequencing or subtyping, there weren’t any new promising therapies, very few clinical trials and treatment centers were working largely in isolation from each other.

We were shocked to learn that scientific collaboration was not the norm, far from it. Academic advancement, competition for the limited available research grants and the rare nature of this disease and corresponding lack of economic incentive for Big Pharma were all forces conspiring against cooperation and collaboration to defeat this monster. Treatments and outcomes had not progressed in over 50 years.

When Dr’s Michael Prados and Sabine Mueller at UCSF asked us to form a non-profit to support a transformative initiative of true collaboration, institutional partnership and information sharing to accelerate discovery, progress, better treatments and ultimately a cure, we didn’t hesitate. PNOC Foundation was formed to exclusively support the work of the PNOC Scientific Consortia.

-- Bruce and Allyn Campbell, PNOC Foundation Co-founders

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PNOC trials have contributed to two recent FDA drug approvals for pediatric brain cancer. Two historic achievements!
300+
Dedicated pediatric brain tumor experts from around the world, working together in an unprecedented global collaboration to find cures, faster.
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PNOC brings breakthrough treatment options to children at the world’s best children's hospitals, PNOC participating sites include: Ann & Robert H. Lurie Children’s Hospital of Chicago CHICAGO, IL Children’s Cancer Hospital, Egypt CAIRO, EGYPT Children’s Hospital Los Angeles LOS ANGELES, CA Children’s Minnesota MINNEAPOLIS, MN Children’s National Hospital WASHINGTON, DC Dana-Farber/Boston Children’s Cancer and Blood Disorders Center BOSTON, MA Doernbecher Children’s Hospital Oregon Health & Science University (OHSU) PORTLAND, OR Duke University Medical Center DURHAM, NC John Hunter Hospital NEWCASTLE, AUSTRALIA Johns Hopkins Hospital BALTIMORE, MD Joseph M. Sanzari Children’s Hospital at Hackensack University Medical Center HACKENSACK, NJ Monash Children’s Hospital CLAYTON, AUSTRALIA Nationwide Children’s Hospital COLUMBUS, OH, NYU Langone Health NEW YORK CITY, NY Perth Children’s Hospital PERTH, AUSTRALIA Princess Maxima Center UTRECHT, THE NETHERLANDS Queensland Children’s Hospital BRISBANE, AUSTRALIA Riley Hospital for Children at Indiana University Health INDIANAPOLIS, IN Royal Children’s Hospital Melbourne MELBOURNE, AUSTRALIA Sao Paulo Children’s Hospital SAO PAULO, BRAZIL, St. Jude Children’s Research Hospital MEMPHIS, TN St. Louis Children’s Hospital ST. LOUIS, MO Seattle Children’s Hospital SEATTLE, WA Shaare Zedek Medical Center JERUSALEM, ISRAEL Sydney Children’s Hospital SYDNEY, AUSTRALIA Sheba Medical Center RAMAT GAN, ISRAEL Starship Children’s Hospital AUCKLAND, NEW ZEALAND Tata Memorial Centre, Mumbai MUMBAI, INDIA The Children’s Hospital of Philadelphia PHILADELPHIA, The Children’s Hospital at Westmead WESTMEAD, AUSTRALIA University Children’s Hospital Zürich ZURICH, SWITZERLAND University of Alabama at Birmingham, Children’s of Alabama BIRMINGHAM, ALABAMA University of California, San Diego Rady Children’s Hospital SAN DIEGO, CA UCSF Benioff Children’s Hospitals SAN FRANCISCO, CA University of Michigan – C.S. Mott Children’s Hospital ANN ARBOR, MI University of Florida Shands Children’s Hospital GAINESVILLE, FL University of Utah SALT LAKE CITY, UT Women’s and Children’s Hospital ADELAIDE, AUSTRALIA Children’s Hospital of Michigan DETROIT, MI Huntsman Cancer Center SALT LAKE CITY,​​ UTAH Texas Children’s Hospital HOUSTON, TEXAS University of California, Los Angeles LOS ANGELES, CA Yale University, Yale Cancer Center NEW HAVEN, CT.
$50
Every dollar helps accelerate research towards a future where we lose no child to brain cancer
$500
Help contribute towards developing promising new treatment strategies
$5000
Enroll one child on a PNOC clinical trial to access breakthrough treatment options

Financials

$1.8M
2024 Budget
84%Program Spend
5%Management Spend
12%Fundraising Spend
84%
5%
12%
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